Desensitize without cephalosporin t...

Desensitize without cephalosporin testing. This option is supported from practice measures, but requires admission to the intensive care unit, delays reaching "full strength" antibiotic dose, and does not clarify whether patient is allergic to cephalosporins.

Graded cephalosporin challenge without skin testing. This option is safer than starting with a glutted dose, and a full dose can be reached within sum of two units hours. However, there is a medicolegal risk of reaction without desensitization effort, reaching "full strength" is delayed, and the question of cephalosporin allergy is not clarified.

Skin proof with cefuroxime or ceftriaxone. * If negative, give a graded challenge of the proofed cephalosporin. This option appears to be safe based in succession this study, avoids the ne for admission to the intensive care unit, be the effects in a shorter delay (i.e., couple hours) to reaching full antibiotic toughness and clarifies the question of cephalosporin allergy. However, medicolegal issues remain if desensitization is not performed.

*--Recommend from the authors.

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