Caffeine stimulates insulin secreti...

Caffeine stimulates insulin secretion of pancreatic beta solitary abode; squalids In this study, Tuomilehto and colleagues studied the relationship between coffee consumption and the attack of diabetes mellitus in a Finnish population, which has the highest per-capita coffee consumption in the world.

Using three baseline measure and estimates taken in different regions of Finland, the cogitation identified 6,974 men and 7655 women between 35 and 64 years of age who did not have diabetes at baseline. Exclusion criteria included a diagnosis of coronary heart disease or hit and known diabetes at baseline. Participants complet a questionnaire with information in succession medical history, demographics, and lifestyle factors concerning physical activity, smoking habits, and alcohol, coffee and tea consumption. Coffee consumption was categorized as: nothing to 2 cups, 3 to 4 beakers 5 to 6 cups, 7 to 9 beakers or 10 or more draughts daily. Incident cases of diabetes were set through a national registry.

After 12 years, 381 incident cases of diabetes were identified. After adjusting for age and inquiry year, coffee consumption was associated with higher material substance mass index and cigarette smoking, and lower vital current pressure, education level, light occupational physical activity, tea consumption, and alcohol use. The authors rest an inverse association between diabetes and coffee consumption. The findings remained significant in women and were observ as a tend in men after adjusting for the above factors, with a significant reduction in diabetes risk in those who drank at least 10 beakers of coffee per day.

by the agency of combining data for men and women the sex-adjusted, multivariate hazard ratios were 100 076 054 055 and 039 for each of the five coffee consumption categories, respectively. Of note, although filtered and pot-boiled coffee were inversely associated with diabetes incidence, filtered coffee was more powerfully associated than pot-boiled coffee.

This studious mood found an inverse and graded association between coffee consumption and adumbration 2 diabetes. Although several mechanisms mechanisms are postulated, a clear understanding of the way coffee limits diabetes risk is unknown.

CAROLINE WELLBERY, MD

Tuomilehto J et al. Coffee consumption and risk of archetype 2 diabetes mellitus among middle-aged Finnish men and women JAMA March 10 2004;291:1213-9

COPYRIGHT 2004 American Academy of Family Physicians

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