A significant number of somebodys ...

A significant number of somebodys in the United States have diabetes. This number is look fored to increase dramatically over the nearest few years. Diabetes is a risk factor for developing coronary artery disease. Despite new advances in the treatment of coronary artery disease, significant numbers of patients with diabetes are hospitalized each year because of cardiovascular disease. In addition, coronary artery disease is responsible for 80 percent of deaths in [i]role[/i]s with diabetes. One advance in the treatment of coronary artery disease is percutaneous coronary revascularization, nevertheless this treatment has a long-term limitation of restenosis. Patients with diabetes who receive percutaneous coronary interventions are at higher risk for restenosis compared with the general population. Corpus and colleagues evaluated the association between glycemic have the direction of and the incidence of target bottom revascularization in patients with diabetes who are undergoing elective percutaneous coronary intervention.

Patients who were scheduled to receive elective percutaneous coronary interventions at single center were eligible for the meditation Patients with type 2 diabetes who were not beneath control with diet alone were enrolled; nondiabetic patients who had the act constituted the comparison group. Before the measure A1C, lipid panel, and fibrinogen were assessed. The practice and post-procedure medications were based forward standard protocols. Follow-up care was performed by dint of telephone interview and hospital medical record review at six and 12 month after the action Repeat catheterization was performed in patients who had return of symptoms or objective evidence of ischemia. Optimal diabetic direction was defined for this meditation as an A1C of 7 percent or less

There were 179 consecutive patients with diabetes who participated in the meditation along with 60 randomly gooded nondiabetic patients in the govern group. Patients with diabetes who had optimal glycemic sway had similar target revascularization rates compared with the sway group. Patients with diabetes who had an A1C of more than 7 percent had a significantly higher rate of revascularization compared with patients with optimal glycemic have charge of In addition, optimal glycemic ascendency was associated with a significantly lower rate of cardiac rehospitalization and returning angina at the 12-month follow-up An A1C above 7 percent was a significant independent predictor for target sailing craft revascularization.

The authors determine that patients with diabetes who are undergoing elective percutaneous coronary revascularization and have optimal glycemic command have better outcomes than those who do not have well-controlled diabetes. They note that aggressive treatment of diabetes with an A1C goal of 7 percent or les is beneficial in improving clinical issues after percutaneous coronary intervention.

Corpus RA, et al. Optimal glycemic rule is associated with a lower rate of target duct revascularization in treated type II diabetic patients undergoing elective percutaneous coronary intervention. J Am Coll Cardiol January 7 2003;43:8-14

COPYRIGHT 2004 American Academy of Family Physicians

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