The U provender and Drug Administr...

The U provender and Drug Administration (FDA) is warning breastfeeding women not to use domperidone because of safety belong tos The FDA has not approved the put drugs into for any use, but has received reports that women have purchased the remedy from compounding pharmacies and sources in other countries. Domperidone may increase the secretion of prolactin, which is needinessed for lactation. Published reports document case studies of cardiac arrhythmias, cardiac arrest, and unlooked for death in persons receiving an intravenous form of domperidone that has been withdrawn from the market in a number of countries. The remedy is excreted in breast milk and could unmask an infant to unknown risks. The oral form of domperidone still used in an countries to treat gastric disorders has labeling that warns breastfeeding women not to use the remedy The FDA has issued an alert to field personnel to be onward the lookout for attempts to import the medicine Warning letters have been sent to pharmacies that mix products containing domperidone and firms that give the drug. More information is available online at http://www.fda.gov/bbs/topics/answers/2004/ans01292.html.

COPYRIGHT 2004 American Academy of Family Physicians

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