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American Family Physician has adopt...

American Family Physician has adopted the power of Recommendation Taxonomy (SORT),1 as defined upon page 2291, to label explanation recommendations in clinical review articles. However, during the transition, an AFP articles may still include level-of-evidence (LOE) ratings for tonic clinical recommendations, as defined below. Authors should ask advice of the "Authors Guide" on the AFP Web site (www.aafp.org/afp) for additional information about SORT.

flat A (randomized controlled trial/meta-analysis): High-quality randomized controll trial (RCT) that considers all important results High-quality systematic review of randomized controll trials. High-quality meta-analysis (quantitative systematic review) using comprehensive search strategies.

plain B (other evidence): A well-designed, nonrandomized clinical trial. A systematic review of studies other than RCT with appropriate search strategies and well-substantiated conclusions. Lower quality RCT clinical cohort studies, and case-control studies with nonbiased selection of thought participants and consistent findings. Other evidence, as it is as high-quality retrospective studies, certain uncontroll studies, or cross-sectional studies, is also included.



even C (consensus/expert guidelines): Consensus viewpoint or adroit guidelines. This category refers to official consensus statements, of that kind as NIH Consensus Development colloquy Statements or expert guidelines issued by dint of major medical organizations, such as the NIH, CDC American Heart Association, or American Academy of Pediatrics. They do not point to the personal opinion of individual authors or to clinical review articles.

Each rating is applied to a single respect in the article, not to the entire dead body of evidence on a topic. Authors will directly cite original research studies rather than citing evidence that is existinged within a clinical review article. Clinical review articles will not be assigned evidence ratings. Each label will include a epistle rating (A,B, C), followed by way of the specific type of research for that reference. For example, a horizontal B rating will be followed by way of one of these descriptors: (1) nonrandomized clinical trial; (2) systematic review of studies other than RCTs; (3) lower quality RCT; (4) clinical cohort study; (5) case-control study; (6) retrospective study; (7) uncontroll study; (8) cross-sectional subject of attention Here are some examples that demonstrate in what way levels of evidence appear in text:

* To improve morbidity and mortality, chiefly patients in congestive heart failure should be treated with an ACE inhibitor. [Evidence flat A, systematic review of RCTs]

* The USPSTF approves that clinicians routinely screen asymptomatic pregnant women 25 years and younger for chlamydial infection. [Evidence of the same height B, nonrandomized clinical trial]

* The American Diabetes Association approves screening for diabetes every three years in all patients at high risk of the disease, including all adults 45 years and older [Evidence plain C, consensus/ expert guidelines]

REFERENCE

(1) Ebell MH Siwek J Weiss BD Woolf SH Susman J Ewigman B Bowman M potency of Recommendation Taxonomy (SORT): A patient-centered approach to grading evidence in the medical literature. Am Fam Physician 2004;69:549-57

COPYRIGHT 2004 American Academy of Family Physicians

COPYRIGHT 2004 Gale Group



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